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Cytisine (natural alkaloid), also called cytisinicline (marketed form), is extracted from a golden rain tree (Cytisus Laburnum) and has adverse effects similar to those reported for nicotine [1,2]. It is a partial agonist of the α4 β2 nicotinic receptors, which, when stimulated, lead to a moderate release of dopamine, contributing to the control of withdrawal symptoms.
JMIR Res Protoc 2026;15:e76815
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A crowdsourcing open call involves inviting a group of people, such as adult women impacted by cervical cancer, to solve a problem and share selected solutions with the public [19]. This research examines how art uses cultural contexts to enhance health education and promotion, specifically regarding perceptions of HPV vaccination and screening in Nigeria.
JMIR Form Res 2026;10:e76240
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Osteoporosis poses a significant global health concern, affecting approximately 500 million individuals worldwide, and is associated with 37 million fragility fractures annually in people aged over 55 years [1,2]. This burden is expected to escalate with the aging global population, with projections indicating a 310% increase in hip fractures for men and a 240% increase for women by 2050 [3,4].
JMIR Form Res 2026;10:e76216
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Evaluation of Hospice@Home for Home-Based Palliative Care: Development and Usability Pilot Study
Participants received an in-kind compensation in the form of a thermometer valued at 100,000 KRW (approximately US $68) for their participation.
This pilot study employed a mixed methods approach combining quantitative data collection and qualitative interviews with patients and caregivers.
JMIR Form Res 2026;10:e79334
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There has been a shift in critical care from a focus on survival alone to considerations of quality of life and longer-term recovery. The large majority of people with a life-threatening illness that is treated in an intensive care unit (ICU) will now survive. Among these survivors, more than half experience postintensive care syndrome (PICS)—a myriad of physical, emotional, and cognitive challenges which often co-occur [1,2].
JMIR Form Res 2026;10:e66601
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We acknowledge this as a limitation and will report any potentially relevant non-English studies excluded on this basis.
A comprehensive search strategy will be developed in collaboration with a medical librarian and peer reviewed using the Peer Review of Electronic Search Strategies (PRESS) checklist [23]. We will use both controlled vocabulary and free-text terms reflecting the PCC elements.
JMIR Res Protoc 2026;15:e82486
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A key implementation strategy tested was the use of lay health coaches to deliver the program. Here, coaches attended a 3-day in-person workshop where they were trained in motivational interviewing (MI) as well as the diet, exercise, and diabetes content of the program. This strategy was successfully tested with a community-based partner (YMCA) [16,19-21].
JMIR Res Protoc 2026;15:e81195
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We offered a US $25 gift card as compensation for participants who completed all study procedures.
Initially, we planned to conduct this study as a parallel group randomized trial; however, we encountered usability issues with the REFRAME intervention that prevented us from implementing it at the start of our recruitment period. Therefore, we modified our design to a pilot before-and-after (nonrandomized) study with a 1:1 group allocation ratio.
JMIR Form Res 2026;10:e73769
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Identification is a necessary condition for initiating treatment, but it is not sufficient to ensure that a patient receives the most appropriate treatment (or treatments) in a timely fashion. This is particularly important because early warning systems often focus on nonspecific deterioration risk instead of monitoring for a specific syndrome like sepsis [26]. Ideally, early warning systems that flag high-risk patients would additionally supply data-driven treatment recommendations.
JMIR AI 2026;5:e81642
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A systematic sampling procedure to do that is available in the Rep Vig framework, and for the self-triage use case, a representative vignette set is provided in the framework’s validation study [13]. At this stage, researchers should also assign a gold standard solution to each case and define how the possible outputs of a symptom checker are mapped onto these categories.
JMIR Hum Factors 2026;13:e76168
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