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Triaging Casual From Critical—Leveraging Machine Learning to Detect Self-Harm and Suicide Risks for Youth on Social Media: Algorithm Development and Validation Study

Triaging Casual From Critical—Leveraging Machine Learning to Detect Self-Harm and Suicide Risks for Youth on Social Media: Algorithm Development and Validation Study

A qualitative study by Ali et al [30] revealed that youth disclosures range from hyperbolic expressions (without intent) to discussions of others’ SH-S experiences and explicit self-disclosures. Furthermore, previous research has identified distinctions within SH-S, such as differentiating between suicidal ideation, the likelihood of a suicide attempt, and shifts toward suicidal ideation [7].

Sarvech Qadir, Ashwaq Alsoubai, Jinkyung Katie Park, Naima Samreen Ali, Munmun De Choudhury, Pamela Wisniewski

JMIR Ment Health 2026;13:e76051


Developing a Culturally Adapted Digital Health Application for Older Hispanic Adults With Type 2 Diabetes: Protocol for a Qualitative and Pilot Study

Developing a Culturally Adapted Digital Health Application for Older Hispanic Adults With Type 2 Diabetes: Protocol for a Qualitative and Pilot Study

Similar to non-Hispanic White people, approximately 85% of Hispanic people use a smartphone daily [17]. Hispanic adults are outpacing all other groups in smartphone use growth rate. In addition, similar to other groups, Hispanic adults spend approximately 3 hours per day on a smartphone and 1 hour per day on a tablet.

Joshua Caballero, Raymond L Ownby, Henry Nolan Young, Michelle B McElhannon, N M Mahmudul Alam Bhuiya, Kenny H Esho, Russ H Palmer

JMIR Res Protoc 2026;15:e76294


Efficacy, Safety, and Economic Impact of Cytisinicline Maintenance Therapy in Patients Who Are Candidates for Smoking Cessation: Protocol for a Phase IV, Multicenter, Randomized, Open-Label, Controlled, Parallel Clinical Trial (CITISILONG Trial)

Efficacy, Safety, and Economic Impact of Cytisinicline Maintenance Therapy in Patients Who Are Candidates for Smoking Cessation: Protocol for a Phase IV, Multicenter, Randomized, Open-Label, Controlled, Parallel Clinical Trial (CITISILONG Trial)

Cytisine (natural alkaloid), also called cytisinicline (marketed form), is extracted from a golden rain tree (Cytisus Laburnum) and has adverse effects similar to those reported for nicotine [1,2]. It is a partial agonist of the α4 β2 nicotinic receptors, which, when stimulated, lead to a moderate release of dopamine, contributing to the control of withdrawal symptoms.

Carlos Rabade Castedo, Ana Estany-Gestal, Carlos A Jiménez Ruiz, José Ignacio de Granda-Orive, Juan Antonio Riesco-Miranda, María Isabel Cristóbal Fernández, Angela Ramos-Pinedo, Jaime Signes-Costa Miñana, María Inmaculada Gorordo-Unzueta, Agustin Valido-Morales, Jacobo Sellarés -Torres, Eva Cabrera-César, Alejandro Frino-García, Luis Valdés Cuadrado

JMIR Res Protoc 2026;15:e76815


Creative Arts to Enhance Cervical Cancer Awareness Using Art-Based Messages From a Nigerian Crowdsourcing Open Call: Qualitative Thematic Analysis

Creative Arts to Enhance Cervical Cancer Awareness Using Art-Based Messages From a Nigerian Crowdsourcing Open Call: Qualitative Thematic Analysis

A crowdsourcing open call involves inviting a group of people, such as adult women impacted by cervical cancer, to solve a problem and share selected solutions with the public [19]. This research examines how art uses cultural contexts to enhance health education and promotion, specifically regarding perceptions of HPV vaccination and screening in Nigeria.

Abdulhammed O Babatunde, Ekenechukwu Kokelu, Olufunto A Olusanya, Peter Kalulu, Agatha E Wapmuk, Titilola Gbaja-biamila, Temitope Ojo, Ucheoma Nwaozuru, Chisom Obi-Jeff, Onyekachukwu Anikamadu, Folahanmi T Akinsolu, Hong Xian, Jennifer S Smith, Kayode O Ajenifuja, Jason J Ong, Benedict N Azuogu, Collins O Airhihenbuwa, Joseph D Tucker, Oliver C Ezechi, Juliet Iwelunmor

JMIR Form Res 2026;10:e76240


Large Language Models for Supporting Clear Writing and Detecting Spin in Randomized Controlled Trials in Oncology: Comparative Analysis of GPT Models and Prompts

Large Language Models for Supporting Clear Writing and Detecting Spin in Randomized Controlled Trials in Oncology: Comparative Analysis of GPT Models and Prompts

While most research that has looked at the topic has found a substantial prevalence of spin, the exact number varies as it is not always straightforward to differentiate between what constitutes a balanced and comprehensive presentation of the results and what may be an attempt to mislead the reader [3]. The presence of spin has important implications.

Carole Koechli, Fabio Dennstädt, Christina Schröder, Daniel M Aebersold, Robert Förster, Daniel R Zwahlen, Paul Windisch

JMIR Cancer 2026;12:e78221


Evaluation of a Novel Web-Based Active Learning Tool for Primary Care Physicians’ Continuing Professional Development (The Community Fracture Capture Learning Hub): Quantitative Analysis

Evaluation of a Novel Web-Based Active Learning Tool for Primary Care Physicians’ Continuing Professional Development (The Community Fracture Capture Learning Hub): Quantitative Analysis

Osteoporosis poses a significant global health concern, affecting approximately 500 million individuals worldwide, and is associated with 37 million fragility fractures annually in people aged over 55 years [1,2]. This burden is expected to escalate with the aging global population, with projections indicating a 310% increase in hip fractures for men and a 240% increase for women by 2050 [3,4].

Ahmed M Fathalla, Cherie Chiang, Ralph Audehm, Alexandra Gorelik, Shanton Chang, Thang Dao, Christopher J Yates, Steve Snow, Rahul D Barmanray, Sarah Price, Lucy Collins, John D Wark

JMIR Form Res 2026;10:e76216


Using Alcohol and Sleep Sensors to Understand Blackout Risk in Young Adults’ Natural Settings (The Lights Out Study): Protocol for an Intensive Longitudinal Pilot Study

Using Alcohol and Sleep Sensors to Understand Blackout Risk in Young Adults’ Natural Settings (The Lights Out Study): Protocol for an Intensive Longitudinal Pilot Study

Individuals who engage in heavy drinking and report recent AIBs are a particularly “risky” group of young adults who experience AIBs at a rate of about 1 in every 3 drinking days [4]. The frequency with which AIBs occur is of concern given their strong association with experiencing increased numbers of alcohol-related consequences, acutely (eg, sexual violence) and prospectively (eg, alcohol use disorder) [5-12]. A number of risk factors for experiencing AIBs have been identified.

Veronica L Richards, Ashlea Braun, Michael R Sladek, Junru Zhao, Thad Leffingwell, Sydney Newell Chesebro, Julie M Croff

JMIR Res Protoc 2026;15:e83980


Evaluation of Hospice@Home for Home-Based Palliative Care: Development and Usability Pilot Study

Evaluation of Hospice@Home for Home-Based Palliative Care: Development and Usability Pilot Study

Participants received an in-kind compensation in the form of a thermometer valued at 100,000 KRW (approximately US $68) for their participation. This pilot study employed a mixed methods approach combining quantitative data collection and qualitative interviews with patients and caregivers.

So-Hi Kwon, Mikyoung Angela Lee, Young-Joo Kim, Seo-Hye Park, Min-Jeong Lee, Youngmin Han, A-Sol Kim

JMIR Form Res 2026;10:e79334


SMARTCLOTH Prototype for Dietary Management in Patients With Diabetes Mellitus: Tutorial on Human-Centered Design Methodology for Health Care Hardware Development

SMARTCLOTH Prototype for Dietary Management in Patients With Diabetes Mellitus: Tutorial on Human-Centered Design Methodology for Health Care Hardware Development

Data show that in 2024, an estimated 589 million adults were living with DM, a figure that could reach 853 million by 2050. More than 90% of these cases are type 2 diabetes mellitus (T2 DM), making this disease a global public health challenge [2,3].

Jose M Palomares, Rafael Molina-Luque, Fernando León-García, Irene Casares-Rodríguez, María García-Rodríguez, María Pilar Villena Esponera, Guillermo Molina-Recio

J Med Internet Res 2026;28:e75744


Web-Based Group Photovoice Through the Lens of Survivors of Critical Illness Recovery: Photovoice Qualitative Pilot Study

Web-Based Group Photovoice Through the Lens of Survivors of Critical Illness Recovery: Photovoice Qualitative Pilot Study

There has been a shift in critical care from a focus on survival alone to considerations of quality of life and longer-term recovery. The large majority of people with a life-threatening illness that is treated in an intensive care unit (ICU) will now survive. Among these survivors, more than half experience postintensive care syndrome (PICS)—a myriad of physical, emotional, and cognitive challenges which often co-occur [1,2].

A Fuchsia Howard, Kelsey Lynch, Anita David, Rinila Haridas, Leanne M Currie, Sally Thorne, Gregory Haljan

JMIR Form Res 2026;10:e66601